Category: Standard
DNA Nanolithography Enables Highly Ordered Recognition Interface in Microfluidic Chip for Efficient Capture and Release of Circulating Tumor Cells.
Microfluidic chip with nano-scale buildings has proven nice potential, however the fabrication and price points prohibit its software. Right here, we suggest a conceptually new “DNA nanolithography in microfluidic chip” by utilizing sub-10 nm three-dimensional DNA buildings (TDNs) as frameworks with a pendant aptamer on the high vertex (ApTDN-Chip). The nano-scale framework ensures the aptamer …
A microfluidic chip for rapid analysis of DNA melting curves for BRCA2 mutation screening
A microfluidic chip built-in with a microheater and a luminescent temperature sensor for fast, spatial melting curve evaluation was developed and utilized for the screening of a breast most cancers gene fragment. The strategy may detect genetic variations in round three minutes whole for the entire process, which is way quicker than established procedures. A …
Centrifugal microfluidic lab-on-a-chip system with automated sample lysis, DNA amplification and microarray hybridization for identification of enterohemorrhagic Escherichia coli culture isolates
The event of know-how for the fast, automated identification of bacterial tradition isolates may also help regulatory businesses to shorten response occasions in meals security surveillance, compliance, and enforcement in addition to outbreak investigations. Whereas molecular strategies resembling polymerase chain response (PCR) allow the identification of microbial organisms with excessive sensitivity and specificity, they typically …
The universal dual-mode aptasensor for simultaneous determination of different bacteria based on naked eyes and microfluidic-chip together with magnetic DNA encoded probes
It was critically necessary to develop some delicate, handy and on-site strategies for simultaneous assay of various pathogenic micro organism in meals. On this work, a dual-mode aptasensor was established for fulfilling above goals combing colorimetry with microfluidic chip. This as-prepared dual-mode aptasensor not solely realized speedy screening by bare eye on-site, but additionally the …
Design of micromagnetic arrays for on-chip separation of superparamagnetic bead aggregates and detection of a model protein and double-stranded DNA analytes
Magnetically actuated lab-on-a-chip (LOC) applied sciences have enabled fast, extremely environment friendly separation of particular biomarkers and cells from advanced organic samples. Nonlinear magnetophoresis (NLM) is a way that makes use of a microfabricated magnet array (MMA) and a time various exterior magnetic subject to exactly management the transport of superparamagnetic (SPM) beads on the …
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