DNA Nanolithography Enables Highly Ordered Recognition Interface in Microfluidic Chip for Efficient Capture and Release of Circulating Tumor Cells.
Microfluidic chip with nano-scale buildings has proven nice potential, however the fabrication and price points prohibit its software. Right here, we suggest a conceptually new “DNA nanolithography in microfluidic chip” by utilizing sub-10 nm three-dimensional DNA buildings (TDNs) as frameworks with a pendant aptamer on the high vertex (ApTDN-Chip). The nano-scale framework ensures the aptamer …